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... > Nutritional and Metabolic Diseases > Metabolic Diseases > Lipid Metabolism Disorders > Lipid Metabolism, Inborn Errors > Lipidoses > Sphingolipidoses > Leukodystrophy, Globoid Cell
... > Nutritional and Metabolic Diseases > Metabolic Diseases > Metabolism, Inborn Errors > Lipid Metabolism, Inborn Errors > Lipidoses > Sphingolipidoses > Leukodystrophy, Globoid Cell
... > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Metabolism, Inborn Errors > Lipid Metabolism, Inborn Errors > Lipidoses > Sphingolipidoses > Leukodystrophy, Globoid Cell
... > Nutritional and Metabolic Diseases > Metabolic Diseases > Metabolism, Inborn Errors > Lysosomal Storage Diseases > Lysosomal Storage Diseases, Nervous System > Sphingolipidoses > Leukodystrophy, Globoid Cell
... > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Metabolism, Inborn Errors > Lysosomal Storage Diseases > Lysosomal Storage Diseases, Nervous System > Sphingolipidoses > Leukodystrophy, Globoid Cell
... > Nutritional and Metabolic Diseases > Metabolic Diseases > Brain Diseases, Metabolic > Brain Diseases, Metabolic, Inborn > Lysosomal Storage Diseases, Nervous System > Sphingolipidoses > Leukodystrophy, Globoid Cell
... > Nervous System Diseases > Central Nervous System Diseases > Brain Diseases > Brain Diseases, Metabolic > Brain Diseases, Metabolic, Inborn > Lysosomal Storage Diseases, Nervous System > Sphingolipidoses > Leukodystrophy, Globoid Cell
... > Nutritional and Metabolic Diseases > Metabolic Diseases > Metabolism, Inborn Errors > Brain Diseases, Metabolic, Inborn > Lysosomal Storage Diseases, Nervous System > Sphingolipidoses > Leukodystrophy, Globoid Cell
... > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Metabolism, Inborn Errors > Brain Diseases, Metabolic, Inborn > Lysosomal Storage Diseases, Nervous System > Sphingolipidoses > Leukodystrophy, Globoid Cell
Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Heredodegenerative Disorders, Nervous System > Hereditary Central Nervous System Demyelinating Diseases > Leukodystrophy, Globoid Cell
Nervous System Diseases > Neurodegenerative Diseases > Heredodegenerative Disorders, Nervous System > Hereditary Central Nervous System Demyelinating Diseases > Leukodystrophy, Globoid Cell
... > Nervous System Diseases > Central Nervous System Diseases > Brain Diseases > Leukoencephalopathies > Hereditary Central Nervous System Demyelinating Diseases > Leukodystrophy, Globoid Cell
Nervous System Diseases > Demyelinating Diseases > Hereditary Central Nervous System Demyelinating Diseases > Leukodystrophy, Globoid Cell
... > Nutritional and Metabolic Diseases > Metabolic Diseases > Brain Diseases, Metabolic > Brain Diseases, Metabolic, Inborn > Hereditary Central Nervous System Demyelinating Diseases > Leukodystrophy, Globoid Cell
... > Nervous System Diseases > Central Nervous System Diseases > Brain Diseases > Brain Diseases, Metabolic > Brain Diseases, Metabolic, Inborn > Hereditary Central Nervous System Demyelinating Diseases > Leukodystrophy, Globoid Cell
... > Nutritional and Metabolic Diseases > Metabolic Diseases > Metabolism, Inborn Errors > Brain Diseases, Metabolic, Inborn > Hereditary Central Nervous System Demyelinating Diseases > Leukodystrophy, Globoid Cell
... > Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Metabolism, Inborn Errors > Brain Diseases, Metabolic, Inborn > Hereditary Central Nervous System Demyelinating Diseases > Leukodystrophy, Globoid Cell

Preferred term

Leukodystrophy, Globoid Cell  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • beta-Galactosidase Deficiencies, Galactosylceramide
  • beta-Galactosidase Deficiency, Galactosylceramide
  • Cell Leukoencephalopathies, Globoid
  • Cell Leukoencephalopathy, Globoid
  • Deficiencies, Galactocerebrosidase
  • Deficiencies, Galactosylceramide beta-Galactosidase
  • Deficiencies, GALC
  • Deficiency Disease, Galactosylceramidase
  • Deficiency Disease, Galactosylceramide-beta-Galactosidase
  • Deficiency Diseases, Galactosylceramidase
  • Deficiency Diseases, Galactosylceramide-beta-Galactosidase
  • Deficiency, Galactocerebrosidase
  • Deficiency, Galactosylceramide beta-Galactosidase
  • Deficiency, GALC
  • Diffuse Globoid Body Sclerosis
  • Disease, Galactosylceramidase Deficiency
  • Disease, Galactosylceramide-beta-Galactosidase Deficiency
  • Diseases, Galactosylceramidase Deficiency
  • Diseases, Galactosylceramide-beta-Galactosidase Deficiency
  • Galactocerebrosidase Deficiencies
  • Galactocerebrosidase Deficiency
  • Galactosylceramidase Deficiency Disease
  • Galactosylceramidase Deficiency Diseases
  • Galactosylceramide beta-Galactosidase Deficiencies
  • Galactosylceramide beta Galactosidase Deficiency
  • Galactosylceramide beta-Galactosidase Deficiency
  • Galactosylceramide beta Galactosidase Deficiency Disease
  • Galactosylceramide-beta-Galactosidase Deficiency Disease
  • Galactosylceramide-beta-Galactosidase Deficiency Diseases
  • Galactosylceramide Lipidosis
  • Galactosylcerebrosidase Deficiency
  • Galactosylsphingosine Lipidosis
  • GALC Deficiencies
  • GALC Deficiency
  • Globoid Body Sclerosis, Diffuse
  • Globoid Cell Leukodystrophy
  • Globoid Cell Leukoencephalopathies
  • Globoid Cell Leukoencephalopathy
  • Globoid Leukodystrophies
  • Globoid Leukodystrophy
  • Krabbe Disease
  • Krabbe Leukodystrophy
  • Krabbe's Disease
  • Krabbes Disease
  • Krabbe's Leukodystrophy
  • Krabbes Leukodystrophy
  • Leukodystrophies, Globoid
  • Leukodystrophy, Globoid
  • Leukodystrophy, Krabbe
  • Leukodystrophy, Krabbe's
  • Leukoencephalopathies, Globoid Cell
  • Leukoencephalopathy, Globoid Cell
  • Psychosine Lipidosis

Scope note

  • An autosomal recessive metabolic disorder caused by a deficiency of GALACTOSYLCERAMIDASE leading to intralysosomal accumulation of galactolipids such as GALACTOSYLCERAMIDES and PSYCHOSINE. It is characterized by demyelination associated with large multinucleated globoid cells, predominantly involving the white matter of the central nervous system. The loss of MYELIN disrupts normal conduction of nerve impulses.

History note

  • 1974(1963)

In other languages

URI

http://www.yso.fi/onto/mesh/D007965

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