Concept information
...
Central Nervous System Diseases
Central Nervous System Infections
Infectious Encephalitis
Encephalitis, Viral
Infections
Central Nervous System Infections
Central Nervous System Viral Diseases
Encephalitis, Viral
Preferred term
Leukoencephalopathy, Progressive Multifocal
Type
-
Topical Descriptor
Broader concept
Entry terms
- Encephalitis, JC Polyomavirus
- Encephalopathies, JC Polyomavirus
- Encephalopathy, JC Polyomavirus
- JC Polyomavirus Encephalitis
- JC Polyomavirus Encephalopathy
- Progressive Multifocal Leukoencephalopathy
Scope note
- An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
History note
- 1973(1971)
In other languages
-
Finnish
-
etenevä multifokaalinen leukoenkefalopatia
-
leucoencephalopathia multifocalis NAS
-
leukoencephalopathia multifocalis
-
leukoencephalopathia multifocalis progressiva
-
multifokal leukoencefalopati UNS
-
PML
-
progressiivinen multifokaalinen leukoenkefaliitti
-
progressiv multifokal leukoencefalopati
-
tarkemmin määrittämätön multifokaalinen leukoenkefalopatia
-
Swedish
URI
http://www.yso.fi/onto/mesh/D007968
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}