Concept information
Preferred term
Lovastatin
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- 6 Methylcompactin
- 6-Methylcompactin
- Mevinolin
- Monacolin K
Scope note
- A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.
History note
- 88; for MONACOLIN K use LOVASTATIN (NM) 1980-98
In other languages
-
Finnish
-
Lovacol
-
Lovastatin Alternova
-
Lovastatin Hexal
-
Lovastatin Ratiopharm
-
Lovastatin Stada
-
Swedish
URI
http://www.yso.fi/onto/mesh/D008148
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}