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Preferred term

Lymphocyte Activation  

Type

  • Topical Descriptor

Narrower concepts

Entry terms

  • Blastogenesis
  • Blast Transformation
  • Lymphoblast Transformation
  • Lymphocyte Stimulation
  • Lymphocyte Transformation
  • Stimulation, Lymphocyte
  • Transformation, Blast
  • Transformation, Lymphoblast
  • Transformation, Lymphocyte

Note

  • lymphocyte transformation test goes here but do not index under specific agent inducing transformation unless particularly discussed; do not use for neoplastic transformation of lymphocytes ( = CELL TRANSFORMATION, NEOPLASTIC) or viral transformation of lymphocytes ( = CELL TRANSFORMATION, VIRAL); blast transformation in chronic myelogenous leukemia does not go here: index BLAST CRISIS

Scope note

  • Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.

History note

  • 2003 (1969); for BLAST TRANSFORMATION use BLAST CRISIS 1987-1992

In other languages

  • Finnish

  • imusolujen aktivointi
  • imusolujen transformaatio
  • imusolun aktivaatio
  • imusolun aktivointi
  • imusolun transformaatio
  • lymfosyytin transformaatio
  • lymfosyyttien aktivaatio
  • lymfosyyttien aktivointi
  • lymfosyyttien transformaatio
  • Swedish

URI

http://www.yso.fi/onto/mesh/D008213

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