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Concept information

Preferred term

Lymphotoxin-alpha  

Type

  • Topical Descriptor

Entry terms

  • alpha Lymphotoxin
  • alpha-Lymphotoxin
  • Lymphotoxin
  • TNF-beta
  • TNF Superfamily, Member 1
  • Tumor Necrosis Factor beta
  • Tumor Necrosis Factor-beta
  • Tumor Necrosis Factor Ligand Superfamily Member 1

Note

  • for "lymphocytotoxin" use CYTOTOXINS and LYMPHOCYTES

Scope note

  • A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR.

History note

  • 2007 (1974-1977); for TUMOR NECROSIS FACTOR-BETA & TNF-BETA use TUMOR NECROSIS FACTOR 1988-1989

In other languages

URI

http://www.yso.fi/onto/mesh/D008233

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