Concept information
Preferred term
Lymphotoxin-alpha
Type
-
Topical Descriptor
Broader concept
Entry terms
- alpha Lymphotoxin
- alpha-Lymphotoxin
- Lymphotoxin
- TNF-beta
- TNF Superfamily, Member 1
- Tumor Necrosis Factor beta
- Tumor Necrosis Factor-beta
- Tumor Necrosis Factor Ligand Superfamily Member 1
Note
- for "lymphocytotoxin" use CYTOTOXINS and LYMPHOCYTES
Scope note
- A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR.
History note
- 2007 (1974-1977); for TUMOR NECROSIS FACTOR-BETA & TNF-BETA use TUMOR NECROSIS FACTOR 1988-1989
In other languages
-
Finnish
-
lymfotoksiini
-
lymphotoxinum
-
Swedish
URI
http://www.yso.fi/onto/mesh/D008233
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