Concept information
Preferred term
Mechlorethamine
Type
-
Topical Descriptor
Broader concept
Entry terms
- Bis(2-chloroethyl)methylamine
- Chlorethazine
- Chlormethine
- Methylchlorethamine
- Mustine
- Nitrogen Mustard
Scope note
- A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
History note
- MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was NITROGEN MUSTARD N-OXIDE (NM) 1984-91
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D008466
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