Concept information
Preferred term
Methimazole
Type
-
Topical Descriptor
Broader concept
Entry terms
- 1 Methyl 2 mercaptoimidazole
- 1-Methyl-2-mercaptoimidazole
- Mercasolyl
- Mercazolyl
- Merkazolil
- Methylmercaptoimidazole
- Methymazol
- Thiamazole
- Thimazol
- Tiamazol
Scope note
- A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
History note
- 73(68); was see under THYROID ANTAGONISTS 1963-72
In other languages
-
Finnish
-
tiamatsoli
-
Swedish
URI
http://www.yso.fi/onto/mesh/D008713
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