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Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 4 or More Rings > Ergolines > Methysergide
Heterocyclic Compounds > Alkaloids > Ergot Alkaloids > Ergolines > Methysergide

Preferred term

Methysergide  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Dimethylergometrin
  • Methylmethylergonovine

Scope note

  • An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.

History note

  • 65(63); METHYSERGIDE DERIVATIVES was see under METHYSERGIDE 1975-77; was see under ERGOLINES 1969-74

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URI

http://www.yso.fi/onto/mesh/D008784

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