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Carbohydrates > Glycosides > Aminoglycosides > Anthracyclines > Plicamycin
... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Aromatic > Polycyclic Aromatic Hydrocarbons > Naphthacenes > Anthracyclines > Plicamycin
Polycyclic Compounds > Polycyclic Aromatic Hydrocarbons > Naphthacenes > Anthracyclines > Plicamycin

Preferred term

Plicamycin  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Aureolic Acid
  • Mithramycin
  • Mitramycin

Scope note

  • A tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors. Plicamycin is also used to reduce hypercalcemia, especially that due to malignancies.

History note

  • 93; was MITHRAMYCIN 1971-92 (Prov 1971-72)

In other languages

URI

http://www.yso.fi/onto/mesh/D008926

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