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Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 2-Ring > Indoles > Molindone

Preferred term

Molindone  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Hydrochloride, Molindone
  • Moban
  • Molindone Hydrochloride

Scope note

  • An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of CLOZAPINE. (From AMA Drug Evaluations Annual, 1994, p283)

History note

  • 91(72); was see under INDOLES 1972-90

In other languages

URI

http://www.yso.fi/onto/mesh/D008972

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