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Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxidoreductases Acting on CH-NH2 Group Donors > Monoamine Oxidase

Preferred term

Monoamine Oxidase  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Amine Oxidase (Flavin-Containing)
  • MAO
  • Oxidase, Tyramine
  • Tyramine Oxidase

Scope note

  • An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4.

History note

  • 63; for TYRAMINE OXIDASE use MONOAMINE OXIDASE (NM) 1980-98

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URI

http://www.yso.fi/onto/mesh/D008995

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