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Concept information

Preferred term

Myasthenia Gravis  

Type

  • Topical Descriptor

Entry terms

  • Generalized Myasthenia Gravis
  • Muscle Specific Receptor Tyrosine Kinase Myasthenia Gravis
  • Muscle-Specific Receptor Tyrosine Kinase Myasthenia Gravis
  • Myasthenia Gravis, Generalized
  • Myasthenia Gravis, Ocular
  • Ocular Myasthenia Gravis

Note

  • "myasthenia" unqualified in foreign titles is more often MYASTHENIA GRAVIS than MUSCLE WEAKNESS but check text; congenital: consider MYASTHENIC SYNDROMES, CONGENITAL or specifics

Scope note

  • A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

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URI

http://www.yso.fi/onto/mesh/D009157

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