Concept information
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Proteins
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Calcium-Calmodulin-Dependent Protein Kinases
Preferred term
Myosin-Light-Chain Kinase
Type
-
Topical Descriptor
Broader concept
Entry terms
- Kinase, Myosin
- LCK, Myosin
- Myosin Kinase
- Myosin LCK
- Myosin Regulatory Light Chain Kinase
- Myosin Regulatory Light-Chain Kinase
Scope note
- An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and CALMODULIN. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction.
History note
- 87
In other languages
-
Finnish
-
Swedish
-
MLCKas
URI
http://www.yso.fi/onto/mesh/D009219
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