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Concept information

Preferred term

Myosin-Light-Chain Kinase  

Type

  • Topical Descriptor

Entry terms

  • Kinase, Myosin
  • LCK, Myosin
  • Myosin Kinase
  • Myosin LCK
  • Myosin Regulatory Light Chain Kinase
  • Myosin Regulatory Light-Chain Kinase

Scope note

  • An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and CALMODULIN. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction.

History note

  • 87

In other languages

URI

http://www.yso.fi/onto/mesh/D009219

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