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Concept information

Preferred term

Nelson Syndrome  

Type

  • Topical Descriptor

Scope note

  • A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.

History note

  • 1991(1978)

In other languages

URI

http://www.yso.fi/onto/mesh/D009347

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