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Nervous System Diseases > Neuromuscular Diseases > Peripheral Nervous System Diseases > Neuritis > Neuritis, Autoimmune, Experimental
Animal Diseases > Disease Models, Animal > Nervous System Autoimmune Disease, Experimental > Neuritis, Autoimmune, Experimental
... > Investigative Techniques > Models, Theoretical > Models, Biological > Disease Models, Animal > Nervous System Autoimmune Disease, Experimental > Neuritis, Autoimmune, Experimental
Investigative Techniques > Models, Animal > Disease Models, Animal > Nervous System Autoimmune Disease, Experimental > Neuritis, Autoimmune, Experimental
Immune System Diseases > Autoimmune Diseases > Autoimmune Diseases of the Nervous System > Nervous System Autoimmune Disease, Experimental > Neuritis, Autoimmune, Experimental
Nervous System Diseases > Autoimmune Diseases of the Nervous System > Nervous System Autoimmune Disease, Experimental > Neuritis, Autoimmune, Experimental

Preferred term

Neuritis, Autoimmune, Experimental  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Allergic Neuritis, Experimental
  • Autoimmune Neuritis, Experimental
  • Autoimmune Neuropathies, Experimental
  • Autoimmune Neuropathy, Experimental
  • EAN (Experimental Allergic Neuritis)
  • EAN (Experimental Autoimmune Neuritis)
  • Experimental Allergic Neuritis
  • Experimental Autoimmune Neuritis
  • Experimental Autoimmune Neuropathies
  • Experimental Autoimmune Neuropathy
  • Neuritis, Experimental Allergic
  • Neuritis, Experimental Autoimmune
  • Neuropathies, Experimental Autoimmune
  • Neuropathy, Experimental Autoimmune

Note

  • coordinate with GUILLAINE-BARRE SYNDROME if pertinent

Scope note

  • An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)

History note

  • 2005 (1982)

In other languages

URI

http://www.yso.fi/onto/mesh/D009444

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