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Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 2-Ring > Isoquinolines > Nomifensine

Preferred term

Nomifensine  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Linamiphen
  • Nomifensin

Scope note

  • An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)

History note

  • 86(78); was see under ISOQUINOLINES 1978-85

In other languages

URI

http://www.yso.fi/onto/mesh/D009627

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