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Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Somatomedins > Nonsuppressible Insulin-Like Activity
Biological Factors > Intercellular Signaling Peptides and Proteins > Insulin-Like Peptides > Somatomedins > Nonsuppressible Insulin-Like Activity
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Insulin-Like Peptides > Somatomedins > Nonsuppressible Insulin-Like Activity
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Insulin-Like Peptides > Somatomedins > Nonsuppressible Insulin-Like Activity

Preferred term

Nonsuppressible Insulin-Like Activity  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Activity, Nonsuppressible Insulinlike
  • Insulinlike Activity, Nonsuppressible
  • Nonsuppressible Insulinlike Activity
  • NSILA

Note

  • note category; a blood protein mimicking blood insulin

Scope note

  • A blood protein (NSILA) which mimics the biological activity of insulin in serum, but is not suppressed by insulin antibodies. During acid-ethanol extraction of Cohn fraction III, 10% of the activity is found in the supernatant (NSILA-S) and the remaining activity in the precipitate (NSILA-P). The latter is a large molecular compound, much less stable than the soluble fraction. NSILA-S is a more potent growth factor than insulin and exhibits sulfation activity.

History note

  • 77

In other languages

  • NSILA

    Finnish

  • insuliinivasta-aineiden estämätön aktiivisuudeltaan insuliinin kaltainen proteiini

URI

http://www.yso.fi/onto/mesh/D009632

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RDF/XML TURTLE JSON-LD Created 5/19/76, last modified 7/5/06