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Investigative Techniques > Genetic Techniques > Nucleic Acid Hybridization
Chemical Phenomena > Biochemical Phenomena > Nucleic Acid Hybridization

Preferred term

Nucleic Acid Hybridization  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Genomic Hybridization
  • Genomic Hybridizations
  • Hybridization, Genomic
  • Hybridizations, Genomic

Note

  • IM general only; coord NIM with DNA or RNA or specific (IM); IN SITU HYBRIDIZATION & IN SITU HYBRIDIZATION, FLUORESCENCE are available

Scope note

  • Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)

History note

  • 72(71)

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URI

http://www.yso.fi/onto/mesh/D009693

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