Concept information
Preferred term
Ochronosis
Type
-
Topical Descriptor
Broader concept
Scope note
- The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).
In other languages
URI
http://www.yso.fi/onto/mesh/D009794
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