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Concept information

Preferred term

Oligomycins  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Oligomycin

Scope note

  • A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).

History note

  • 82; was OLIGOMYCIN 1963-81 (Prov 1963-65)

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URI

http://www.yso.fi/onto/mesh/D009840

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