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Concept information

Preferred term

Paraproteins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Paraprotein

Scope note

  • Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered.

History note

  • 76; was see under GLOBULINS 1963-65

In other languages

URI

http://www.yso.fi/onto/mesh/D010266

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