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Concept information

Genetic Phenomena > Mutagenesis > Translocation, Genetic > Philadelphia Chromosome

Preferred term

Philadelphia Chromosome  

Type

  • Topical Descriptor

Entry terms

  • 1 Chromosomes, Ph
  • Chromosome, Ph 1
  • Chromosome, Ph1
  • Chromosomes, Ph 1
  • Chromosomes, Ph1
  • Ph 1 Chromosome
  • Ph1 Chromosome
  • Ph 1 Chromosomes
  • Ph1 Chromosomes

Scope note

  • An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).

History note

  • 86; was see CHROMOSOMES, HUMAN, 21-22 1978-85

In other languages

URI

http://www.yso.fi/onto/mesh/D010677

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