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Concept information

Preferred term

Lactase-Phlorizin Hydrolase  

Type

  • Topical Descriptor

Entry terms

  • Lactase Glycosylceramidase
  • Lactase-Glycosylceramidase

Scope note

  • A multifunctional protein that contains two enzyme domains. The first domain (EC 3.2.1.62) hydrolyzes glycosyl-N-acylsphingosine to a sugar and N-acylsphingosine. The second domain (EC 3.2.1.108) hydrolyzes LACTOSE and is found in the intestinal brush border membrane. Loss of activity for this enzyme in humans results in LACTOSE INTOLERANCE.

History note

  • 2014 (1992)

In other languages

URI

http://www.yso.fi/onto/mesh/D010694

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