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... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Fructokinases > Phosphofructokinases > Phosphofructokinase-1

Preferred term

Phosphofructokinase-1  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • 6-Phosphofructo-1-kinase
  • 6 Phosphofructokinase
  • 6-Phosphofructokinase
  • Fructose-6-P 1-Kinase
  • Fructose-6-phosphate 1-Phosphotransferase

Note

  • general or unspecified; prefer specifics

Scope note

  • An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues.

History note

  • 2002

In other languages

URI

http://www.yso.fi/onto/mesh/D010732

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