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Concept information

Preferred term

Viral Plaque Assay  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Assay, Bacteriophage Plaque
  • Assays, Bacteriophage Plaque
  • Bacteriophage Plaque Assay
  • Bacteriophage Plaque Assays
  • Plaque Assay, Bacteriophage
  • Plaque Assays, Bacteriophage

Note

  • for viruses; coord IM or NIM with specific virus /growth (IM); do not confuse with HEMOLYTIC PLAQUE TECHNIQUE in immunol

Scope note

  • Method for measuring viral infectivity and multiplication in CULTURED CELLS. Clear lysed areas or plaques develop as the VIRAL PARTICLES are released from the infected cells during incubation. With some VIRUSES, the cells are killed by a cytopathic effect; with others, the infected cells are not killed but can be detected by their hemadsorptive ability. Sometimes the plaque cells contain VIRAL ANTIGENS which can be measured by IMMUNOFLUORESCENCE.

History note

  • 2012 (1973)

In other languages

URI

http://www.yso.fi/onto/mesh/D010948

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