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Biological Factors > Blood Coagulation Factors > Plasminogen Activators > Tissue Plasminogen Activator
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Blood Coagulation Factors > Plasminogen Activators > Tissue Plasminogen Activator
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Serine Endopeptidases > Plasminogen Activators > Tissue Plasminogen Activator
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Serine Proteases > Serine Endopeptidases > Plasminogen Activators > Tissue Plasminogen Activator

Preferred term

Tissue Plasminogen Activator  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Alteplase
  • Plasminogen Activator, Tissue Type
  • Plasminogen Activator, Tissue-Type
  • Tisokinase
  • Tissue Activator D 44
  • Tissue Activator D-44
  • Tissue Type Plasminogen Activator
  • Tissue-Type Plasminogen Activator
  • T Plasminogen Activator
  • T-Plasminogen Activator
  • TTPA

Scope note

  • A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.

History note

  • 98(86)

In other languages

  • TPA

    Finnish

  • kudoksen plasminogeenin aktivaattori
  • T-PA
  • Vävnadsplasminogenaktivator

    Swedish

  • Actilyse
  • Alteplas
  • Cellplasminogenaktivator
  • Kärlaktivator
  • Vävnadsaktivator

URI

http://www.yso.fi/onto/mesh/D010959

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RDF/XML TURTLE JSON-LD Created 6/12/85, last modified 7/1/16