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Concept information

Preferred term

Platelet Factor 4  

Type

  • Topical Descriptor

Entry terms

  • Antiheparin Factor
  • Chemokine CXCL4
  • Chemokine, CXCL4
  • CXCL4 Chemokine
  • CXCL4, Chemokine
  • gamma Thromboglobulin
  • gamma-Thromboglobulin
  • Heparin Neutralizing Protein
  • PF4 (Platelet Factor 4)

Scope note

  • A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.

History note

  • 84(76); was see under BLOOD COAGULATION FACTORS 1976-83

In other languages

URI

http://www.yso.fi/onto/mesh/D010978

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