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Lipids > Lipopeptides > Polymyxins > Polymyxin B
Amino Acids, Peptides, and Proteins > Peptides > Lipopeptides > Polymyxins > Polymyxin B
Amino Acids, Peptides, and Proteins > Peptides > Peptides, Cyclic > Polymyxins > Polymyxin B
Polycyclic Compounds > Macrocyclic Compounds > Peptides, Cyclic > Polymyxins > Polymyxin B
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Pore Forming Cytotoxic Proteins > Antimicrobial Cationic Peptides > Polymyxins > Polymyxin B
... > Amino Acids, Peptides, and Proteins > Peptides > Antimicrobial Peptides > Antimicrobial Cationic Peptides > Polymyxins > Polymyxin B

Preferred term

Polymyxin B  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Aerosporin
  • Polymyxin B Sulfate

Scope note

  • A mixture of polymyxins B1 and B2, obtained from BACILLUS POLYMYXA strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for treatment of infections with gram-negative bacteria, but may be neurotoxic and nephrotoxic.

History note

  • 1991(1978); was see under POLYMYXINS 1978-90; was AEROSPORIN see under POLYMYXIN 1971-77, see POLYMYXIN 1963-70; AEROSPORIN was see POLYMYXIN B 1978-93

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URI

http://www.yso.fi/onto/mesh/D011112

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