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Concept information

Preferred term

Prekallikrein  

Type

  • Topical Descriptor

Entry terms

  • Factor, Fletcher
  • Fletcher Factor
  • Kallikreinogen
  • Plasma Prokallikrein
  • Prokallikrein, Plasma

Scope note

  • A plasma protein which is the precursor of kallikrein. Plasma that is deficient in prekallikrein has been found to be abnormal in thromboplastin formation, kinin generation, evolution of a permeability globulin, and plasmin formation. The absence of prekallikrein in plasma leads to Fletcher factor deficiency, a congenital disease.

History note

  • 89(76); was see under KALLIKREINS 1976-88

In other languages

URI

http://www.yso.fi/onto/mesh/D011288

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