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Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Pro-Opiomelanocortin
... > Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Neuropeptides > Hypothalamic Hormones > Pro-Opiomelanocortin
Amino Acids, Peptides, and Proteins > Peptides > Neuropeptides > Hypothalamic Hormones > Pro-Opiomelanocortin
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Peptide Hormones > Hypothalamic Hormones > Pro-Opiomelanocortin
Amino Acids, Peptides, and Proteins > Peptides > Peptide Hormones > Hypothalamic Hormones > Pro-Opiomelanocortin
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Peptide Hormones > Pituitary Hormones > Pituitary Hormones, Anterior > Pro-Opiomelanocortin
... > Amino Acids, Peptides, and Proteins > Peptides > Peptide Hormones > Pituitary Hormones > Pituitary Hormones, Anterior > Pro-Opiomelanocortin

Preferred term

Pro-Opiomelanocortin  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • ACTH beta Lipotropin Precursor
  • ACTH-beta-Lipotropin Precursor
  • ACTH Endorphin Precursor
  • ACTH-Endorphin Precursor
  • Corticotropin beta Lipotropin Precursor
  • Corticotropin-beta-Lipotropin Precursor
  • Endorphin ACTH Precursor
  • Endorphin-ACTH Precursor
  • POMC
  • Pro ACTH Endorphin
  • Pro-ACTH-Endorphin
  • Pro Opiocortin
  • Pro-Opiocortin
  • Proopiocortin
  • Pro Opio Melanocortin
  • Pro-Opio-Melanocortin
  • Proopiomelanocortin

Scope note

  • A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).

History note

  • 1985

In other languages

URI

http://www.yso.fi/onto/mesh/D011333

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