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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Metalloendopeptidases > Procollagen N-Endopeptidase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Metalloproteases > Metalloendopeptidases > Procollagen N-Endopeptidase

Preferred term

Procollagen N-Endopeptidase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Procollagen N Proteinase
  • Procollagen N-Proteinase
  • Procollagen Peptidase

Scope note

  • An extracellular endopeptidase which excises a block of peptides at the amino terminal, nonhelical region of the procollagen molecule with the formation of collagen. Absence or deficiency of the enzyme causes accumulation of procollagen which results in the inherited connective tissue disorder--dermatosparaxis. EC 3.4.24.14.

History note

  • 97; was PROCOLLAGEN PEPTIDASE 1977-96 (see under ENDOPEPTIDASES 1977-90)

In other languages

URI

http://www.yso.fi/onto/mesh/D011348

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