Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Nutritional and Metabolic Diseases > Metabolic Diseases > Metabolism, Inborn Errors > Progeria
Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Metabolism, Inborn Errors > Progeria
Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Laminopathies > Progeria

Preferred term

Progeria  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Hutchinson Gilford Progeria Syndrome
  • Hutchinson-Gilford Progeria Syndrome
  • Hutchinson-Gilford Progeria Syndromes
  • Hutchinson Gilford Syndrome
  • Hutchinson-Gilford Syndrome
  • Progeria Syndrome, Hutchinson-Gilford
  • Progeria Syndromes, Hutchinson-Gilford

Scope note

  • An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature graying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

In other languages

  • progeria

    Finnish

  • Hutchinson-Gilford
  • Hutchinson-Gilfordin oireyhtymä
  • Hutchinson-Gilfordin syndrooma
  • syndroma Hutchinson-Gilfordin
  • Progeri

    Swedish

URI

http://www.yso.fi/onto/mesh/D011371

Download this concept:

RDF/XML TURTLE JSON-LD Created 1/1/99, last modified 2/21/20