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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Dioxygenases > Prolyl Hydroxylases > Procollagen-Proline Dioxygenase
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Prolyl Hydroxylases > Procollagen-Proline Dioxygenase

Preferred term

Procollagen-Proline Dioxygenase  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • 4-Hydroxylase, Procollagen Prolyl
  • Hydroxylase, Protocollagen Prolyl
  • Procollagen Prolyl 4 Hydroxylase
  • Procollagen Prolyl 4-Hydroxylase
  • Prolyl 4-Hydroxylase, Procollagen
  • Prolyl Hydroxylase, Protocollagen
  • Protocollagen Prolyl Hydroxylase

Scope note

  • A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl containing peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular OXYGEN with a concomitant oxidative decarboxylation of 2-oxoglutarate to SUCCINATE. The enzyme occurs as a tetramer of two alpha and two beta subunits. The beta subunit of procollagen-proline dioxygenase is identical to the enzyme PROTEIN DISULFIDE-ISOMERASES.

History note

  • 94; was PROLINE HYDROXYLASE 1972-93 (Prov 1972-73); PROLINE,2-OXOGLUTARATE 4-DIOXYGENASE was PROLINE,2-OXOGLUTARATE DIOXYGENASE see PROLINE HYDROXYLASE 1977-93

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URI

http://www.yso.fi/onto/mesh/D011393

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