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Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Protamines
Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > Protamines

Preferred term

Protamines  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Protamine

Note

  • heparin antag

Scope note

  • A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)

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URI

http://www.yso.fi/onto/mesh/D011479

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