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Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Protein Kinase C
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Protein Kinase C
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Protein Kinase C

Preferred term

Protein Kinase C  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Calcium Activated Phospholipid Dependent Kinase
  • Calcium-Activated Phospholipid-Dependent Kinase
  • Calcium Phospholipid Dependent Protein Kinase
  • Calcium Phospholipid-Dependent Protein Kinase
  • Phospholipid-Dependent Kinase, Calcium-Activated
  • Phospholipid Sensitive Calcium Dependent Protein Kinase
  • Phospholipid-Sensitive Calcium-Dependent Protein Kinase
  • PKC Serine Threonine Kinase
  • PKC Serine-Threonine Kinase
  • Serine-Threonine Kinase, PKC

Scope note

  • An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.

History note

  • 86; CALCIUM PHOSPHOLIPID-DEPENDENT PROTEIN KINASE was CALCIUM-PHOSPHOLIPID DEPENDENT PROTEIN KINASE 1986-93

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URI

http://www.yso.fi/onto/mesh/D011493

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