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... > Enzymes and Coenzymes > Enzymes > Transferases > Acyltransferases > Aminoacyltransferases > Transglutaminases

Preferred term

Transglutaminases  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Gamma-Glutamyltransferases, Glutaminyl-Peptide
  • gamma-Glutamyltransferases, Protein-Glutamine
  • Glutaminyl Peptide Gamma Glutamyltransferases
  • Glutaminyl-Peptide Gamma-Glutamyltransferases
  • Protein Glutamine gamma Glutamyltransferases
  • Protein-Glutamine gamma-Glutamyltransferases
  • Transglutaminase

Note

  • distinguish entry terms GLUTAMINYL-PEPTIDE GAMMA-GLUTAMYLTRANSFERASES, and TRANSGLUTAMINASES from GAMMA-GLUTAMYL TRANSPEPTIDASE which is involved with glutathione metabolism; PLASMA TRANSGLUTAMINASE see FACTOR XIIIA is also available

Scope note

  • Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.

History note

  • 2002(1986)

In other languages

URI

http://www.yso.fi/onto/mesh/D011503

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