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Concept information

Preferred term

Prothrombin  

Type

  • Topical Descriptor

Entry terms

  • Blood Coagulation Factor II
  • Coagulation Factor II
  • Differentiation Reversal Factor
  • Factor, Differentiation Reversal
  • Factor II
  • Factor II, Coagulation
  • II, Coagulation Factor

Note

  • a blood coag factor; an enzyme precursor

Scope note

  • A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.

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URI

http://www.yso.fi/onto/mesh/D011516

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