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Immune System Diseases > Purpura, Thrombocytopenic > Purpura, Thrombotic Thrombocytopenic
... > Pathological Conditions, Signs and Symptoms > Signs and Symptoms > Skin Manifestations > Purpura > Purpura, Thrombocytopenic > Purpura, Thrombotic Thrombocytopenic
... > Pathological Conditions, Signs and Symptoms > Pathologic Processes > Hemorrhage > Purpura > Purpura, Thrombocytopenic > Purpura, Thrombotic Thrombocytopenic
... > Hemic and Lymphatic Diseases > Hematologic Diseases > Blood Coagulation Disorders > Purpura > Purpura, Thrombocytopenic > Purpura, Thrombotic Thrombocytopenic
... > Hemic and Lymphatic Diseases > Hematologic Diseases > Blood Platelet Disorders > Thrombocytopenia > Thrombotic Microangiopathies > Purpura, Thrombocytopenic > Purpura, Thrombotic Thrombocytopenic
... > Hemic and Lymphatic Diseases > Hematologic Diseases > Cytopenia > Thrombocytopenia > Thrombotic Microangiopathies > Purpura, Thrombocytopenic > Purpura, Thrombotic Thrombocytopenic
Hemic and Lymphatic Diseases > Hematologic Diseases > Thrombophilia > Purpura, Thrombotic Thrombocytopenic

Preferred term

Purpura, Thrombotic Thrombocytopenic  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Moschcowitz Disease
  • Moschkowitz Disease
  • Purpura, Thrombotic Thrombopenic
  • Thrombopenic Purpura, Thrombotic
  • Thrombotic Thrombocytopenic Purpura
  • Thrombotic Thrombopenic Purpura

Scope note

  • An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases.

History note

  • 1986; use PURPURA, THROMBOTIC THROMBOPENIC 1965-1985

In other languages

  • tromboottinen trombosytopeeninen purppura

    Finnish

  • microangiopathia thrombotica
  • Moschcowitz
  • Moschcowitzin oireyhtymä
  • Moschcowitzin sairaus
  • Moschcowitzin syndrooma
  • Moschcowitzin tauti
  • purpura thrombocytopenica thrombotica
  • tromboottinen mikroangiopatia
  • trombosytopeeninen tromboottinen purppura
  • TTP
  • Trombotisk trombocytopen purpura

    Swedish

  • Familjär trombotisk mikroangiopati
  • Moschcowitz sjukdom
  • Upshaw-Schulman syndrom

URI

http://www.yso.fi/onto/mesh/D011697

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