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Preferred term

Pyrrolizidine Alkaloids  

Type

  • Topical Descriptor

Narrower concepts

Entry terms

  • Alkaloid, Pyrrolizidine
  • Pyrrolizidine Alkaloid

Scope note

  • A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.

History note

  • 73(71)

In other languages

URI

http://www.yso.fi/onto/mesh/D011763

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