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Enzymes and Coenzymes > Enzymes > Ligases > Carbon-Carbon Ligases > Pyruvate Carboxylase

Preferred term

Pyruvate Carboxylase  

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  • Topical Descriptor

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Scope note

  • A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and animals. Deficiency of this enzyme causes severe psychomotor retardation and ACIDOSIS, LACTIC in infants. EC 6.4.1.1.

History note

  • 74

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http://www.yso.fi/onto/mesh/D011766

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