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... > Enzymes and Coenzymes > Enzymes > Lyases > Carbon-Carbon Lyases > Carboxy-Lyases > Pyruvate Decarboxylase

Preferred term

Pyruvate Decarboxylase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 2 Oxo Acid Carboxy Lyase
  • 2-Oxo Acid Carboxy-Lyase
  • Acid Carboxy-Lyase, 2-Oxo
  • alpha Carboxylase
  • alpha-Carboxylase
  • alpha Ketoacid Carboxylase
  • alpha-Ketoacid Carboxylase
  • Carboxylase, alpha-Ketoacid
  • Carboxy-Lyase, 2-Oxo Acid
  • Decarboxylase, Pyruvic
  • Pyruvic Decarboxylase

Scope note

  • Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1.

History note

  • 91(75); was see under CARBOXY-LYASES 1975-90

In other languages

URI

http://www.yso.fi/onto/mesh/D011767

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