Concept information
Preferred term
Quinidine
Type
-
Topical Descriptor
Broader concept
Entry terms
- Chinidin
Scope note
- An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
URI
http://www.yso.fi/onto/mesh/D011802
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