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Concept information

Preferred term

Receptors, Cell Surface  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Cell Surface Receptor
  • Cell Surface Receptors
  • Receptor, Cell Surface
  • Surface Receptor, Cell

Note

  • general or unspecified; prefer specifics; coord IM with specific endogenous substance (IM); for hormone receptors in general coord HORMONES (IM) and RECEPTORS, CELL SURFACE (IM) or RECEPTORS, CYTOPLASMIC AND NUCLEAR (IM), for receptors of specific hormones, coord specific hormone or hormone group (IM) and precoord hormone receptor (e.g., RECEPTORS, ALDOSTERONE) (IM) or precoord hormone-group receptor (e.g., RECEPTORS, GLUCOCORTICOID) (IM)

Scope note

  • Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands.

History note

  • 94; was RECEPTORS, ENDOGENOUS SUBSTANCES 1983-93; was RECEPTORS, HORMONE 1973-82; CELL RECEPTORS & RECEPTORS, BIOLOGIC were see RECEPTORS, ENDOGENOUS SUBSTANCES 1985-93; HORMONE RECEPTORS was see RECEPTORS, ENDOGENOUS SUBSTANCES 1975-93

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URI

http://www.yso.fi/onto/mesh/D011956

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