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Concept information

Preferred term

Receptors, Thyroid Hormone  

Type

  • Topical Descriptor

Entry terms

  • Thyroid Hormone Receptor
  • Thyroid Hormone Receptors

Note

  • coordinate with specific thyroid hormone

Scope note

  • Specific high affinity binding proteins for THYROID HORMONES in target cells. They are usually found in the nucleus and regulate DNA transcription. These receptors are activated by hormones that leads to transcription, cell differentiation, and growth suppression. Thyroid hormone receptors are encoded by two genes (GENES, ERBA): erbA-alpha and erbA-beta for alpha and beta thyroid hormone receptors, respectively.

History note

  • 87; PROTO-ONCOGENE PROTEIN ERBA was (NM) 1987-93

In other languages

URI

http://www.yso.fi/onto/mesh/D011988

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