Concept information
Preferred term
Renin
Type
-
Topical Descriptor
Broader concept
Entry terms
- Angiotensin Forming Enzyme
- Angiotensin-Forming Enzyme
- Angiotensinogenase
Note
- do not confuse with RENNIN see CHYMOSIN
Scope note
- A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
History note
- 1963; for PRORENIN use RENIN (NM) 1977-2003, for PREPRORENIN use RENIN (NM) 1980-2003
URI
http://www.yso.fi/onto/mesh/D012083
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