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Concept information

Preferred term

Renin  

Type

  • Topical Descriptor

Entry terms

  • Angiotensin Forming Enzyme
  • Angiotensin-Forming Enzyme
  • Angiotensinogenase

Note

  • do not confuse with RENNIN see CHYMOSIN

Scope note

  • A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.

History note

  • 1963; for PRORENIN use RENIN (NM) 1977-2003, for PREPRORENIN use RENIN (NM) 1980-2003

In other languages

URI

http://www.yso.fi/onto/mesh/D012083

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