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Concept information

Pathological Conditions, Signs and Symptoms > Pathologic Processes > Nerve Degeneration > Retrograde Degeneration

Preferred term

Retrograde Degeneration  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Axonal Reaction
  • Axonal Reactions
  • Axon Reaction
  • Axon Reactions
  • Degeneration, Nissl
  • Nissl Degeneration
  • Reaction, Axon
  • Reaction, Axonal
  • Reactions, Axon
  • Reactions, Axonal

Scope note

  • Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons.

History note

  • 91(75); was see under NERVE DEGENERATION 1975-90; NISSL DEGENERATION was see NERVE DEGENERATION 1997, was heading 1975-96 (see under NERVE DEGENERATION 1975-90)

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URI

http://www.yso.fi/onto/mesh/D012183

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