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Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 4 or More Rings > Rifamycins > Rifampin
Polycyclic Compounds > Macrocyclic Compounds > Lactams, Macrocyclic > Rifamycins > Rifampin
... > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Lactams > Lactams, Macrocyclic > Rifamycins > Rifampin
... > Organic Chemicals > Amides > Lactams > Lactams, Macrocyclic > Rifamycins > Rifampin

Preferred term

Rifampin  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Benemycin
  • Rifampicin

Scope note

  • A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)

History note

  • 73

In other languages

  • rifampisiini

    Finnish

  • rifampicinum
  • rifampiini
  • Rimapen
  • RMP
  • Rifampin

    Swedish

  • Rifadin
  • Rifampicin
  • Rimactan

URI

http://www.yso.fi/onto/mesh/D012293

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