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Organic Chemicals > Hydrocarbons > Terpenes > Diterpenes > Ryanodine
Heterocyclic Compounds > Alkaloids > Ryanodine
Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Azoles > Pyrroles > Ryanodine

Preferred term

Ryanodine  

Type

  • Topical Descriptor

Broader concept

Scope note

  • A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.

History note

  • 91(75); was see under ALKALOIDS 1975-90

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URI

http://www.yso.fi/onto/mesh/D012433

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