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Concept information

Preferred term

Secretory Component  

Type

  • Topical Descriptor

Entry terms

  • Secretory Piece

Scope note

  • The extracellular moiety of the POLYMERIC IMMUNOGLOBULIN RECEPTOR found alone or complexed with IGA or IGM, in a variety of external secretions (tears, bile, colostrum.) Secretory component is derived by proteolytic cleavage of the receptor during transcytosis. When immunoglobulins IgA and IgM are bound to the receptor, during their transcytosis secretory component becomes covalently attached to them generating SECRETORY IMMUNOGLOBULIN A or secretory IMMUNOGLOBULIN M.

History note

  • 91(76); was see under IMMUNOGLOBULIN FRAGMENTS 1976-90

In other languages

URI

http://www.yso.fi/onto/mesh/D012635

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