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Preferred term

Sex Hormone-Binding Globulin  

Type

  • Topical Descriptor

Entry terms

  • Binding Globulin, Testosterone-Estradiol
  • Globulin, Testosterone-Estradiol Binding
  • Sex Steroid Binding Protein
  • Sex Steroid-Binding Protein
  • Steroid-Binding Protein, Sex
  • Testosterone Estradiol Binding Globulin
  • Testosterone-Estradiol Binding Globulin

Note

  • does not refer to all sex hormones: refers to a specific protein in the blood binding only testosterone or estradiol; for other sex hormone-binding globulins consider ANDROGEN-BINDING PROTEIN & PROGESTERONE-BINDING GLOBULIN

Scope note

  • A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.

History note

  • 77; SEX STEROID-BINDING PROTEIN was SEX-STEROID-BINDING PROTEIN (NM) 1981-91; ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN were see SEX HORMONE-BINDING GLOBULIN 1977-92

In other languages

URI

http://www.yso.fi/onto/mesh/D012738

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